Magnesium Glycinate: Benefits, Doses & Side Effects

Magnesium glycinate is a highly bioavailable supplement formed by combining the essential mineral magnesium with the amino acid glycine. This unique composition allows for easy absorption, making it a popular choice among magnesium supplements.

Research shows that magnesium glycinate may offer several health benefits. It is known to help relieve anxiety, improve sleep quality, promote bone health, support gut health, and enhance athletic performance. 

As you explore the world of magnesium supplementation, magnesium glycinate stands out as a versatile and easily absorbed option to support various aspects of your health.

Keep in mind, though, that it’s crucial to consult with a healthcare professional before starting any new supplement regimen.

What Is Magnesium Glycinate?

Magnesium glycinate is a highly-absorbable form of magnesium supplement. It consists of the mineral magnesium and is paired with the amino acid glycine. This combination results in a superior bioavailability compared to other magnesium types.

Essential Mineral

As a supplement, magnesium glycinate helps boost your body’s magnesium levels. This essential mineral plays a critical role in many body functions, such as regulating blood pressure and aiding in protein synthesis.

The amino acid glycine supports the efficacy of magnesium glycinate. It facilitates magnesium absorption by the body and enhances its overall benefits. Together, magnesium and glycine create a powerful compound to address various health issues.

Easily Absorbed Supplement

Magnesium Glycinate is a supplemental form of magnesium that has excellent absorption rates. Its optimal bioavailability is attributed to the presence of glycine, an amino acid that aids in the transportation of magnesium across intestinal walls.

This supplement’s high absorbability isn’t its only perk. It’s gentler on the stomach compared to other magnesium forms because it doesn’t require stomach acid for absorption. This makes Magnesium Glycinate a top choice for users with sensitive digestion.

Magnesium Deficiency

If you have a magnesium deficiency, you may experience a range of symptoms. It is important to note that magnesium deficiency is relatively rare in healthy individuals eating a balanced diet. 

Many individuals have lower magnesium levels than advised, but they might not be aware of it since the signs of low magnesium can often go unnoticed.

Some common symptoms include muscle weakness, irregular heartbeat, nausea, and vomiting. If you experience these symptoms, consult your healthcare provider.

Benefits Of Magnesium Glycinate

Magnesium Glycinate is a prominent form of magnesium lauded for its superior absorption rates and numerous health benefits. Let’s delve into its advantages.

Relieves Anxiety

Magnesium Glycinate can function as a natural relaxant, assisting in alleviating anxiety. It supports the nervous system by curbing stress responses and promoting calmness, subsequently bringing relief from anxiety symptoms.

Furthermore, the amino acid glycine in Magnesium Glycinate promotes relaxation. It helps in controlling the transmission of nerve impulses in your brain, which aids in reducing anxiety and enhancing sleep quality.

Promotes Bone Health

Magnesium Glycinate plays a pivotal role in maintaining bone health. Magnesium is necessary for adequate calcium absorption, a mineral integral to building and strengthening bones. Deficiency in magnesium correlates with lower bone density levels.

Regular supplementation of Magnesium Glycinate can thus aid in reducing the risks associated with bone disorders like osteoporosis. 

Its proper absorption ensures that sufficient magnesium reaches your bones to enhance their health and longevity.

Manages Blood Sugar

Magnesium Glycinate is known for its role in managing blood sugar levels. Magnesium plays a crucial function in carbohydrate metabolism and insulin’s action in the body, helping to regulate and stabilize blood sugar levels.

By supporting the body’s insulin function, Magnesium Glycinate can contribute to the avoidance or management of type 2 diabetes. This makes it a valuable supplement for individuals concerned about blood sugar control and related health conditions.

Reduces High Blood Pressure

Magnesium Glycinate contributes to the reduction of high blood pressure. Magnesium aids in relaxing blood vessels, thereby contributing to maintaining normal blood pressure levels and promoting overall cardiovascular health.

Consistent intake of Magnesium Glycinate can thus help in managing hypertension. Its capacity to mitigate high blood pressure makes this supplement beneficial for people prone to cardiovascular diseases.

Improves Sleep Patterns

Magnesium Glycinate has been recognized for its role in improving sleep patterns. The glycine in this supplement can encourage relaxation and promote better sleep quality by reducing instances of insomnia and facilitating a restful night’s sleep.

Moreover, magnesium’s relation to the regulation of neurotransmitters aids in managing the body’s sleep cycle. Hence, using a Magnesium Glycinate supplement might result in an improved sleep pattern for many individuals.

Alleviates Muscle Cramps

Magnesium Glycinate can provide relief from muscle cramps. Magnesium’s role in neuromuscular transmission and muscle contraction suggests that its deficiency can cause muscle cramps, making this supplement a potential remedy.

Additionally, Magnesium Glycinate’s excellent absorption properties ensure sufficient magnesium is accessible for muscular function. Regular intake can alleviate muscle cramps and improve muscle strength, as well as function–a significant benefit for athletes and older people.

Support Optimal Energy Levels

Magnesium is involved in multiple biochemical processes related to energy production. Hence, its adequacy is vital to sustaining bodily energy levels.

Its high bioavailability ensures the body receives sufficient magnesium to facilitate these energy-generation processes, thereby benefiting your day-to-day activities.

Recommended Supplement Use

Magnesium glycinate supplements come in various forms, such as capsules, pills, or powders. To use them, follow the recommended dosage instructions on the product packaging closely.

Take with Meals

Taking magnesium glycinate with meals enhances its absorption, minimizing potential gastrointestinal side effects. 

Furthermore, pairing with food can prevent stomach upset, a common concern when starting supplementation. 

Increase Water Intake

Make sure to drink plenty of water when consuming magnesium glycinate supplements. Increasing water intake when consuming magnesium glycinate can aid digestion and absorption.

Additionally, staying hydrated can counteract potential side effects like dehydration and kidney stress.


The dosage of Magnesium Glycinate varies depending on individual health needs and goals. However, a standard recommended dosage often falls between 200-400 mg per day. It’s crucial to follow the instructions given by your healthcare provider or on the supplement package.

Remember, taking more than the recommended dosage can lead to adverse effects. Always consult with a healthcare provider before starting any new supplement regimen, especially if you’re taking medications or have underlying health conditions.

Side Effects

As with any supplement, some side effects may occur. Some common side effects of magnesium glycinate supplementation include mild diarrhea and stomach discomfort. If you experience severe or persistent side effects, discontinue use and consult your healthcare provider.

As with all supplements, monitor your experience and adjust your intake based on your individual needs and side effects.

Magnesium Toxicity Precautions

When you consume too much magnesium glycinate, your body might experience some side effects. 

Gastrointestinal Disturbance

Magnesium supplements, including magnesium glycinate, can occasionally cause gastrointestinal disturbances. One common symptom of excess magnesium intake is diarrhea. 

This can lead to stomach upset and make you feel uncomfortable. Other symptoms might include bloating or stomach cramps, especially when taken in large doses.

It’s essential to monitor for such symptoms and adjust dosage accordingly.

Kidney Function

Additionally, high magnesium levels can affect your kidney function. Your kidneys work to filter out excess magnesium from your bloodstream. If your magnesium levels are too high, this could put a strain on your kidneys and cause related issues. 

It is essential to monitor your magnesium intake and keep it within the recommended range. 

Risks of Taking Magnesium

Magnesium, a vital mineral, is generally safe for most individuals when consumed in recommended amounts. However, excessive intake or certain forms may pose risks, warranting an understanding of its potential side effects.

Interactions with Medicines

Magnesium supplements can interact with certain medications, such as antibiotics. If you’re taking any medications, consult with your doctor or healthcare professional before starting magnesium supplementation.

They can provide guidance on whether magnesium glycinate is the right choice for you and ensure that it won’t harm your health.

Health Considerations

When taken in high doses, magnesium supplements can cause side effects, such as nausea, abdominal cramping, and diarrhea. Individuals with kidney disease, high blood pressure, or type 2 diabetes should be cautious when using magnesium supplements.

Pregnant women and individuals with osteoporosis should also consult with their healthcare professional before using magnesium glycinate.

Natural Sources Of Magnesium

Magnesium is an essential mineral, and your body requires it for numerous processes. To maintain healthy magnesium levels, you should consume a balanced diet that includes various magnesium-rich foods.

Nuts and Seeds

Nuts and seeds are excellent natural sources of magnesium. Almonds, cashews, and Brazil nuts are particularly high in magnesium. A handful of these can provide a substantial portion of the recommended daily intake.

Seeds like flax, pumpkin, and chia are also rich in magnesium. Incorporating them into your diet can contribute to maintaining your body’s magnesium levels while enjoying a nutritional power boost.


Beans are a significant natural source of magnesium. Varieties like black beans, kidney beans, and chickpeas provide a healthy dose of magnesium, along with being an excellent source of fiber and protein.

Regularly including beans in your diet contributes to meeting your daily magnesium needs. Their versatility in dishes makes it easy to incorporate them into different meals, supporting a nutrient-rich diet.

Leafy Green Vegetables

Leafy green vegetables like spinach, kale, and collard greens are packed with magnesium. They contribute significantly to fulfilling the recommended daily intake of this mineral, in addition to their broad spectrum of other essential nutrients.

These nutrient-dense greens can be included in your diet in a variety of ways, providing a range of health benefits alongside their rich magnesium content. Consuming them on a regular basis can help maintain optimal magnesium levels in the body.


Fish, particularly fatty ones like salmon, mackerel, and halibut, are considerable natural sources of magnesium. Their high magnesium content aids in fulfilling the daily dietary requirement of this vital mineral.

Not only is fish a rich source of magnesium, but they’re also packed with Omega-3 fatty acids and lean proteins, which support heart health. Including fish in your diet can provide a boost of essential nutrients, including magnesium.

Whole Grains

Whole grains such as brown rice, quinoa, and whole wheat bread are rich in magnesium. They serve as a fulfilling and nutritious way to meet your daily magnesium needs.

Including whole grains in your diet not only provides you with the necessary magnesium but also offers other benefits like improved digestion and heart health. Their high dietary fiber content, along with the presence of various other vitamins and minerals, make them a healthy staple in any diet.

Frequently Asked Questions

What are the common side effects of magnesium glycinate?

While magnesium glycinate is generally well-absorbed and less likely to cause stomach upset, some common side effects may include diarrhea, stomach pain, and nausea.

If you experience severe symptoms, consult your healthcare provider.

Which foods are rich in magnesium glycinate?

Magnesium glycinate is a supplement, not a food-source nutrient. However, you can find magnesium in foods like leafy greens, nuts, seeds, whole grains, and legumes.

Consuming magnesium-rich foods can contribute to maintaining healthy magnesium levels.

How does magnesium glycinate help with anxiety?

Magnesium glycinate may help alleviate anxiety by promoting relaxation and reducing stress.

Research suggests that maintaining adequate magnesium levels can support a healthy nervous system and contribute to overall mental well-being.

Are there any interactions between magnesium glycinate and other medications?

Yes, magnesium glycinate can interact with certain medications, such as antibiotics and diuretics.

To avoid potential interactions, discuss your supplement use with your healthcare provider, especially if you are taking any prescription medications.

What is the optimal timing for taking magnesium glycinate?

It’s best to take magnesium glycinate with a meal to reduce the risk of stomach upset.

For optimal absorption, follow the product instructions or your healthcare provider’s recommendations regarding timing and dosage.