Anemia: Symptoms, Causes, Diagnosis & Treatment

Iron deficiency is one of the most common nutritional deficiencies, and its effects on the body are wide-ranging. When your iron levels are low, one surprising area that can be affected is your eye health.

Anemia is characterized by a shortage of red blood cells or a hemoglobin deficiency, impairing the body’s ability to transport oxygen effectively.

Understanding the signs of anemia is the first step towards addressing its root causes and enhancing overall well-being.

The Role of Iron in Your Body

Understanding the role of iron in your body can help you appreciate its importance for optimal health. We’ll provide you with a comprehensive overview of iron’s crucial roles and impact on your well-being.

Red Blood Cell Production

Iron plays a pivotal role in the production of hemoglobin, a protein present in your red blood cells.

It’s this protein that effectively carries oxygen from your lungs and distributes it to the rest of your body, aiding in organ function and overall health.

Food to Energy Conversion

The role of iron extends to your body’s energy metabolism as well. It actively contributes towards the creation of ATP (adenosine triphosphate), which happens to be your body’s primary source of energy.

A shortage of iron can thus impact this function, leading to feelings of exhaustion and lethargy. In effect, a deficiency could curb your physical stamina, limiting your capacity to go about daily tasks with normal energy levels.

Body’s Immunity

Iron’s contributions further span the upkeep of your immune system. It enables the healthy development and differentiation of immune cells.

These cells come into play when your body must tackle pathogens or foreign substances, offering you protection against sickness.

Brain Development and Function

Iron is essential for the development and function of the brain. It plays a role in neurotransmitter synthesis and myelin formation, which is crucial for nerve signal transmission.

Insufficient iron levels may lead to impaired cognitive function, affecting memory, concentration, and overall mental acuity.

Eye Health

Iron plays a crucial role in your eye health. It is essential in creating the choroid and retina, which are responsible for visual sharpness and depth perception. Without enough iron, your eyes may not function properly.

Additionally, iron deficiency can lead to vision problems. Anemia, a condition often related to iron deficiency, can cause dark spots, blurred vision, and light sensitivity. So incorporating iron into your diet is vital for good eye health.

Creation of DNA Molecules

Iron is intricately tied to DNA synthesis. It aids in the function of enzymes responsible for the creation of DNA, which forms the genetic blueprint of your cells.

Iron also notably impacts cellular growth and division too. 

An iron deficiency can dampen these processes, potentially affecting your body’s ability to grow and repair tissues optimally.

Common Causes of Iron Deficiency

In order to manage your health, it’s essential to understand the common causes of iron deficiency. By familiarizing yourself with these, you can take preventive measures and make informed decisions about your well-being.

Lack of Iron in Diet

Iron deficiency can arise when your dietary intake of iron is insubstantial.

This is often the case for individuals following a strictly vegetarian or vegan diet, as the type of iron found in plants is less readily absorbed by the body.

Even those consuming a diverse diet may need more iron intake and to include iron-rich foods like red meat, poultry, or fortified cereals in their regular meals.

Impaired Iron Absorption

Even with sufficient dietary iron, you can still develop an iron deficiency if your body struggles to absorb this crucial mineral.

Certain conditions like celiac disease, or surgical procedures such as gastric bypass, can impair your body’s ability to absorb iron. Medications like antacids or proton pump inhibitors can also interfere with iron absorption. Consequently, even a diet rich in iron might not always prevent an iron deficit.

Blood Loss

Iron deficiency often stems from blood loss. Conditions that cause significant bleeding, like heavy menstrual periods and regular use of non-steroidal anti-inflammatory drugs (NSAIDs), can lead to an iron-deficient state.

Even slow, chronic blood loss within the body, such as from a peptic ulcer, a hiatus hernia, a colon polyp, or colorectal cancer can deplete your body’s iron stores without you noticing the impact until anemia sets in.

Pregnancy or Breastfeeding

Pregnancy and breastfeeding are other common causes of iron deficiency. Iron requirements surge during pregnancy due to the increased blood volume and the growing baby’s needs.

Similarly, breastfeeding can deplete maternal iron stores as iron is transported to the baby through breast milk. Therefore, it’s important during these periods to get enough iron, either through diet or supplements.

Signs and Symptoms of Iron Deficiency

Understanding iron deficiency is crucial in maintaining your overall well-being. Iron is an essential mineral, and when your iron levels dwindle, certain symptoms and health problems can arise.

This section will guide you in recognizing iron deficiency signs and symptoms to help you take care of your health.

Pale Skin

An individual lacking adequate iron may have a noticeably paler complexion. Hemoglobin gives blood its red color, so if you have fewer red blood cells, your skin can lose its natural, healthy color.

The pallor usually affects the entire body. You might notice it first on your face, particularly your lips, gums, inside your mouth, or your lower eyelids, which can appear lighter than usual.

Cold Hands and Feet

Cold hands and feet are a common symptom of anemia, primarily attributed to impaired oxygen transport in the bloodstream.

Insufficient oxygen levels can lead to vasoconstriction, reducing blood flow to extremities and causing the sensation of coldness.

Brittle Nails

Changes in the texture and appearance of nails, like brittleness or spoon-shaped deformities, are observable signs.

Brittle nails are a potential indicator of anemia, a condition often linked to iron deficiency. Inadequate iron levels can affect nail health, causing them to become weak, brittle, and prone to splitting. 

Problems with Vision

If you’re iron deficient, one common symptom is blurred vision. This happens because low iron levels can disrupt the proper function of the muscles and nerves in your eyes.

Another noticeable symptom could be pale or yellowish eyes. Iron deficiency can result in anemia, which often makes the whites of the eyes appear less white or even yellow.

Keep in mind that these symptoms could indicate other health issues, so it’s important to consult a healthcare professional.

Fatigue and Weakness

Iron deficiency can make you feel exhausted and weak. As your body struggles to produce enough hemoglobin due to a lack of iron, your tissues, and muscles may not get enough oxygen, thus leading to persistent fatigue.

Physical weakness is another common symptom that often accompanies fatigue. You may feel as if extra effort is required to perform everyday tasks or physical activities, which can significantly affect your quality of life.

Difficulty in Breathing

Iron deficiency can also lead to shortness of breath. This is due to the body not being able to transport enough oxygen to its cells. You might feel breathless or have trouble catching your breath, especially after physical activities that you were previously able to do with ease.

Under severe conditions, you might also have difficulty breathing even while at rest. This symptom should not be ignored as it can seriously affect your day-to-day functions and life.

Irregular Heartbeat

Palpitations, or awareness of the heartbeat, are symptoms that may arise as the heart rate compensates for decreased oxygen-carrying capacity.

In severe cases, chest pain or angina can be a symptom of anemia straining the heart.

Challenges with Thinking and Brain Function

A lesser-known effect of iron deficiency is cognitive impairment. Since iron contributes to oxygen provision to the brain, an iron-deficient body might struggle to maintain optimal brain function. 

This can manifest as difficulty concentrating, poor memory, headaches, dizziness, light-headedness, or general mental fatigue. 

Children with iron deficiency can therefore experience developmental delays, and adults may face reduced productivity and safety risks.

Diagnosing Iron Deficiency

Usually, identifying low iron levels involves a visit to your doctor and specific tests. These determine if you’re experiencing iron deficiency.

Complete Blood Count and Other Tests

The most common way to diagnose iron deficiency is through a series of blood tests.

The Complete Blood Count (CBC) can give a hint about the possibility of iron deficiency by indicating lower-than-normal levels of hemoglobin and hematocrit.

Furthermore, specific tests such as serum iron, transferrin, and ferritin levels can provide a more precise diagnosis of iron deficiency. These tests measure the amount of iron stored and transported in your body.

Deficiencies in vitamin B12 or folate can cause specific types of anemia. Blood tests can determine levels of these vitamins too.

Physical Examination and Medical History

A physician may also perform a physical examination to detect signs of iron deficiency. This could include checking for a pale complexion, quickened pulse, unusual heart sounds, or an enlarged spleen.

Moreover, your doctor may review your health history, dietary habits, and any symptoms of fatigue, weakness, or breathlessness to identify signs that point toward an iron deficiency. Discussing your medical history can be instrumental in forming a comprehensive diagnosis.

Additional Blood Sampling

A microscopic examination of a blood smear is done to assess the size, shape, and characteristics of red blood cells, providing additional information about the type of anemia.

Reticulocytes are young, immature red blood cells. Measuring their count can help determine if the bone marrow is responding appropriately to the need for more red blood cells.

Additional Tests

In some instances, your physician may recommend procedures like an endoscopy or colonoscopy to identify potential sources of blood loss that could be causing iron deficiency. These procedures involve the use of a flexible tube to inspect your digestive tract.

While invasive, these procedures can be essential in detecting if issues such as ulcers, polyps, or tumors in your stomach, intestines, or colon are adding to your iron deficiency.

If your doctor suspects you may have celiac disease, a blood test can help diagnose this condition. The specific diagnostic approach depends on the type of anemia suspected and the individual’s clinical presentation. 

A healthcare professional will interpret the results and recommend appropriate interventions based on the underlying cause and severity of the anemia.

Treatment and Management

Effective management of iron levels hinges on a tailored approach towards iron supplementation, diet modification, underlying condition treatment, and vigilance against possible complications.

Iron Supplements

Iron supplements are among the primary treatment methods for iron deficiency. They are typically prescribed by your doctor and help restore your body’s iron levels more rapidly than dietary changes alone.

However, iron supplements can cause certain side effects such as constipation, nausea, or an upset stomach. It’s important to discuss these potential side effects and the proper dosage with your doctor before starting any supplement regimen.

Changes in Meal Planning

Adjusting your diet to include more iron-rich foods can also help treat and prevent iron deficiency. Foods such as red meat, poultry, seafood, legumes, fortified cereals, and leafy green vegetables are rich in iron.

Pairing iron-rich foods with sources of vitamin C, which aids in iron absorption, can enhance their effectiveness. Conversely, try to avoid consuming iron with substances that hinder iron absorption, including coffee, tea, and dairy products.

Direct Iron Therapy through the Vein

In severe cases or when oral supplements are ineffective or cause unacceptable side effects, intravenous iron therapy can be an option. This involves supplying iron directly into your bloodstream through an IV drip.

This method can quickly replenish your iron stores. However, it carries possible side effects, such as allergic reactions. Decisions regarding IV iron therapy should be made carefully in consultation with your healthcare provider.

Blood Transfusion

In cases of severe anemia or acute blood loss, blood transfusions may be necessary to boost red blood cell levels quickly.

Treating Underlying Causes

If iron deficiency is a result of an underlying health issue – like an ulcer, tumor, celiac disease, or heavy menstrual bleeding – treating the underlying condition is vital in combating your iron deficiency.

In certain cases, your doctor may recommend medication, surgery, or other treatments for the root cause of your iron deficiency. These treatments should be tailored to your individual circumstances and managed by a healthcare professional.

Frequently Asked Questions

How does iron deficiency affect the body’s energy and metabolism?

The role of iron extends to the body’s energy metabolism. It actively contributes towards the creation of ATP (adenosine triphosphate), which is the body’s primary source of energy.

Therefore, a shortage of iron can impact this function, leading to feelings of exhaustion and lethargy and may limit the capacity to go about daily tasks with normal energy levels.

What tests are usually carried out to diagnose iron deficiency?

A physical examination is initially carried out to check for signs of iron deficiency. Iron deficiency is usually diagnosed through a series of blood tests, including the Complete Blood Count (CBC), serum iron, transferrin, and ferritin levels.

In some instances, doctors may also recommend procedures like endoscopy, colonoscopy, or a blood test for Celiac disease, to have an idea if there is an underlying condition.

What are the most common causes of iron deficiency?

Some common causes of iron deficiency include inadequate iron intake, which often happens when individuals follow a strictly vegetarian or vegan diet or when they fail to include iron-rich foods in their regular meals.

Iron deficiency can also be caused by poor iron absorption due to medical conditions or certain medications, significant bleeding from conditions like heavy menstrual periods, ulcers, and regular use of NSAIDs, and conditions related to pregnancy and breastfeeding.

How is iron deficiency usually treated and managed?

Iron deficiency is usually treated and managed through various methods, though the exact treatment method will depend on the individual’s circumstances and should be managed by a healthcare professional.

These include iron supplementation prescribed by a doctor and dietary changes to include more iron-rich foods.

Intravenous iron therapy and blood transfusion are considered for severe cases and for treating any underlying causes that are leading to iron deficiency.